Brought to you by the letter "Control-Option-A".
Before my VoiceOver adventures began, I would tutor my clients on the use of standard shortcut keys and how to discover new keys by looking at the menus. The key-combinations are listed to the right of each menu item. Most of the often-used keys involved the use of the Command key on Mac, or the Control key on Windows. On the Mac, hold down Command with your thumb and press "s" and the current document will be saved. Look at the File menu, next to the "Save" menu item is "Command-s." Simple, right?