I am a developer of the app Speech Central, which is available for all Apple's devices (Mac, iPhone, iPad, Apple Watch, Apple TV).
On Mac this is a comprehensive text to speech app that can take all sort of inputs - web (but not just web articles but also web pages with headlines that are shown in an interactive way so that you can add interesting articles right from those reading pages), documents (pdf, docx, pptx, html, eml, txt, OpenOffice), e-books (epub, fb2) and both speak aloud those forms or saving them into the .m4a format. Also the app supports annotation of those texts like bookmarking the paragraphs or marking whole the texts as favorite for easier retrieval using the filters and search.
I would appreciate if someone could take a look into the app (I can provide several users with a free code to get the app) and provide his honest opinion regarding how helpful this app is regarding the accessibility here https://www.applevis.com/node/add/mac-app-directory . I am also committed to improve the app according to the feedback from those users.
You can take a more detailed look on the app at the Mac App Store: https://itunes.apple.com/us/app/speech-central-text-to-speech-suite/id1223093645?mt=12